This is day 7 homework, the last one for BIC by 生信星球.
The content for today is the introduction of DNA sequencing.
1. three generations of DNA sequencing technologies
1.1 1st generation: Sanger method is the most successful one.
1.2 2nd generation: NGS, is currently one of the most popular techniques.
Roche-454 GS FLX
Illumina solexa genome analyzer
ABI SOLiD sequencer
1.3 3rd generation: none-emplication, long reading, single molecule sequencing, however high erra rate at 10-15%
PacBio SMRT
Oxford Naopore Technologies
This is a good review from Genomics 2016 Jan;107(1):1-8.
The sequence of sequencers: The history of sequencing DNA by
James M Heather, Benjamin Chainfiliations expand
DOI: 10.1016/j.ygeno.2015.11.003
The end
